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Condition

Carbonic Anhydrase VI Deficiency

Carbonic anhydrase VI deficiency is a shortage or malfunction of an enzyme in saliva that helps balance mouth acidity, buffers acid that would otherwise wear at teeth, and supports taste buds. Little research on supplements for it has been reviewed here so far, so there are no trial findings to report yet. Because the condition is rare and under-recognized, what is known about oral health support comes mostly from studies of the wider population rather than people with this deficiency.

Supplements studied
1
Graded outcomes
0
Trials
1
People studied
14

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Zinc

Zinc: outcomes studied for Carbonic Anhydrase VI Deficiency
GradeOutcomeEffectSizeStudiesPeopleStudies list
Dysgeusia

Improvement

Improves (the measure goes up)1 study

Studies that measured dysgeusia

The Carbonic Anhydrase VI Deficiency Supportive Care protocol

2 primary supplements · 5 supporting supplements

  • Zinc15–30 mg daily (zinc picolinate or citrate)
  • Probiotics (Oral/Dental)10–20 billion CFU daily (Lactobacillus, Streptococcus salivarius)

See the full protocol

Studies cited

1 study from PubMed

  1. Efficacy of exogenous oral zinc in treatment of patients with carbonic anhydrase VI deficiencyAm J Med Sci · PMID 10616164