Condition
Graves’ Disease
Graves' disease is an autoimmune condition in which the body makes antibodies that push the thyroid to produce too much thyroid hormone, and it is the most common cause of an overactive thyroid. Among supplements, vitamin D has the clearest trial finding: bone density improved in people after Graves' disease treatment. The evidence is limited, though, and it comes from a small number of small studies.
Sources: PMID 39264438
- Supplements studied
- 1
- Graded outcomes
- 1
- Trials
- 1
- People studied
- 86
Evidence by supplement
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Bone Mineral Density Small Improvement | Improves (the measure goes up) | Small effect | 2 studies | 86 people | ||
Studies that measured bone mineral density
| ||||||
Key findings
- Bone Mineral DensityImproves (the measure goes up)
The Graves' Disease Supportive Care protocol
2 primary supplements · 4 supporting supplements
Studies cited
2 studies from PubMed
- Changes in bone density and microarchitecture following treatment of Graves' disease and the effects of vitamin D supplementation. A randomized clinical trial.
- Efficacy of combination therapy of vitamin D and bisphosphonates in the treatment of postmenopausal osteoporosis: a systematic review and meta-analysis.