Condition
Hemorrhoids
Hemorrhoids are swollen blood vessels in and around the rectum and anus that can itch, bleed or hurt. The evidence is strongest for fiber and diosmin, and a pooled analysis of 22 trials found a diosmin-based blend lowered bleeding, pain and swelling after hemorrhoid surgery, with horse chestnut moderate. That blend result mostly applies to people recovering from surgery, and the horse chestnut evidence comes from work on vein problems more broadly.
- Supplements studied
- 3
- Graded outcomes
- 1
- Trials
- 2
- People studied
- 642
Evidence by supplement
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Hemorrhoid Symptoms Meta-analysis (22 RCTs, n=2335): MPFF improved clinical efficacy post-hemorrhoidectomy, reduced bleeding rate (0.9% vs 6.1%, p=0.03), pain score, and edema score. Dose: 3000mg/day for 3 days then 1500mg/day for 4 days. | Improves (the measure goes down) | Moderate effect |
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Hemorrhoids Symptoms | Improves (the measure goes down) | 1 study | 72 people | |||
Studies that measured hemorrhoids symptoms | ||||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Hemorrhoids Symptoms | Improves (the measure goes down) | 1 study | 570 people | |||
Key findings
- Hemorrhoid SymptomsImproves (the measure goes down)
The Hemorrhoids Support protocol
2 primary supplements · 3 supporting supplements
- Fiber Supplement20–35 g total fiber daily (supplement + diet)
- Diosmin/Hesperidin (Flavonoids)500 mg diosmin + 50 mg hesperidin twice daily
Shop the evidence-backed picks
The collection holds the supplements we grade A or B for its theme, in products from the Fullscript catalog. It opens in our Fullscript store. You can look through it without signing in; Fullscript asks for a free account to order.
We earn from purchases made in our Fullscript store, and links to Fullscript, iHerb or Thorne carry our referral, so we may earn a commission at no extra cost to you. Grades come from the research and never change based on what we earn. Full disclosure
Studies cited
2 studies from PubMed