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Condition

Kashin-Beck Disease (KBD)

Kashin-Beck disease is a long-lasting bone and joint disorder found in parts of China, Siberia, and North Korea, in which cartilage breaks down and damages bone, causing joint pain, stiffness, and shortened fingers and limbs in children. Little research on supplements for it has been reviewed here so far, so there are no trial findings to report yet. Selenium deficiency is a major contributing factor, alongside possible grain mycotoxins and low iodine.

Supplements studied
1
Graded outcomes
0
Trials
2
People studied
434

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Glucosamine: outcomes studied for Kashin-Beck Disease (KBD)
GradeOutcomeEffectSizeStudiesPeopleStudies list
Kashin-Beck Disease SymptomsImproves (the measure goes down)2 studies434 people

The Kashin-Beck Disease Supportive Care protocol

2 primary supplements · 6 supporting supplements

See the full protocol

Studies cited

2 studies from PubMed

  1. Chondroitin sulfate and/or glucosamine hydrochloride for Kashin-Beck disease: a cluster-randomized, placebo-controlled studyOsteoarthritis Cartilage · PMID 22469850
  2. Kashin-Beck disease in Sichuan, China: report of a pilot open therapeutic trialJ Clin Rheumatol · PMID 22157279