Skip to content
Winnowleaf home

Condition

Tardive Dyskinesia (TD)

Tardive dyskinesia is a movement disorder of involuntary, repetitive movements, often in the face, tongue, and jaw, that can develop after long-term use of certain psychiatric medications, especially older antipsychotics. Vitamin E and vitamin B6 have the most research behind them, and some studies found signs of benefit for symptoms, though the evidence for each is limited. The studies were modest in size, and vitamin E seemed less helpful once the movements were already established.

Supplements studied
1
Graded outcomes
1
Trials
1
People studied
157

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Ginkgo Biloba: outcomes studied for Tardive Dyskinesia (TD)
GradeOutcomeEffectSizeStudiesPeopleStudies list
Serum BDNF

Small Increase

Improves (the measure goes up)Small effect157 people
Tardive Dyskinesia SymptomsImproves (the measure goes down)1 study157 people

Key findings

  • Serum BDNFGinkgo BilobaImproves (the measure goes up)

The Tardive Dyskinesia Supportive Care protocol

2 primary supplements · 3 supporting supplements

See the full protocol

Studies cited

1 study from PubMed

  1. Brain-derived neurotrophic factor levels and its Val66Met gene polymorphism predict tardive dyskinesia treatment response to Ginkgo bilobaBiol Psychiatry · PMID 22695185