Condition
Tardive Dyskinesia (TD)
Tardive dyskinesia is a movement disorder of involuntary, repetitive movements, often in the face, tongue, and jaw, that can develop after long-term use of certain psychiatric medications, especially older antipsychotics. Vitamin E and vitamin B6 have the most research behind them, and some studies found signs of benefit for symptoms, though the evidence for each is limited. The studies were modest in size, and vitamin E seemed less helpful once the movements were already established.
- Supplements studied
- 1
- Graded outcomes
- 1
- Trials
- 1
- People studied
- 157
Evidence by supplement
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Serum BDNF Small Increase | Improves (the measure goes up) | Small effect | 157 people | |||
| Tardive Dyskinesia Symptoms | Improves (the measure goes down) | 1 study | 157 people | |||
Studies that measured tardive dyskinesia symptoms | ||||||
Key findings
- Serum BDNFImproves (the measure goes up)
The Tardive Dyskinesia Supportive Care protocol
2 primary supplements · 3 supporting supplements
- Vitamin E400–1,600 IU daily
- Vitamin B6100–400 mg daily
Studies cited
1 study from PubMed