Supplement
Cangfu Daotan Decoction is a traditional Chinese herbal formula, made from several plants and used for irregular cycles. In women with polycystic ovary syndrome and infertility, meta-analyses of Chinese trials found that adding it to clomiphene gave higher ovulation and pregnancy rates than clomiphene alone. The evidence is limited, though, since the trials varied widely, carried a risk of bias, and were of low quality.
- Updated
- How we grade
- Best evidence
- Grade C
- Conditions studied
- 1
- Outcomes
- 2
- Graded outcomes
- 0020
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Ovulation Rate Meta-analyses of Chinese RCTs: CFDTD + clomiphene improved ovulation rates vs clomiphene alone in PCOS patients. Evidence quality is low due to methodological limitations. | Improves (the measure goes up) | Moderate effect | 1,200 people | |||
| Pregnancy Rate Meta-analysis: Higher pregnancy rates when CFDTD added to clomiphene treatment for PCOS-related infertility. Studies have high heterogeneity and risk of bias. | Improves (the measure goes up) | Moderate effect | 900 people |
Key findings
- Ovulation RateImproves (the measure goes up)
- Pregnancy RateImproves (the measure goes up)
Safety notes in the studies
- Studies have high heterogeneity and risk of bias.