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Supplement

Phosphatidylcholine

Phosphatidylcholine is a fat-like molecule that helps build the membranes surrounding every cell, including liver cells, where it supports repair and normal function. People mostly look at it for general liver health, and the evidence for that use is moderate. Still, the research summarized here did not include specific liver results, and cholesterol measures in 152 people, HDL and LDL, showed no clear difference.

Best evidence
Grade D
Conditions studied
1
Outcomes
4
Graded outcomes
0002

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

1 condition

General Cardiovascular Health

General Cardiovascular Health: outcomes studied for Phosphatidylcholine
GradeOutcomeEffectSizeStudiesPeopleStudies list
High-density lipoprotein (HDL)

No effect

NoneNo effect152 people
Low-density lipoprotein (LDL)

No effect

NoneNo effect152 people
Total cholesterolImproves (the measure goes down)152 people
TriglyceridesImproves (the measure goes down)152 people

Key findings

  • High-density lipoprotein (HDL)
  • Low-density lipoprotein (LDL)

Studies cited

1 study from PubMed

  1. Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humansPLoS Med · PMID 15916468