Supplement
Pramiracetam is a lab-made compound from the racetam family, thought to influence acetylcholine, a brain messenger involved in memory. People mostly look at it for memory, and the evidence is limited: two small studies found memory improved. Those studies included just 35 people in total, and one involved young men with memory problems after head injury, so the results say little about healthy adults.
Sources: PMID 1786500; PMID 18653001
- Updated
- How we grade
- 3 studies cited
- Best evidence
- Grade C
- Conditions studied
- 3
- Outcomes
- 5
- Graded outcomes
- 0030
Evidence by condition
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Memory Small Improvement | Improves (the measure goes up) | Small effect | 2 studies | 35 people | ||
| Forgetting Small Improvement | Improves (the measure goes up) | Small effect | 1 study | 24 people | ||
Studies that measured forgetting | ||||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Cognition Small Improvement | Improves (the measure goes up) | Small effect | 4 people | |||
| Memory | Improves (the measure goes up) | 2 studies | 4 people | |||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Forgetting | Improves (the measure goes up) | 1 study | 24 people | |||
Studies that measured forgetting | ||||||
Key findings
- MemoryImproves (the measure goes up)
- ForgettingImproves (the measure goes up)
- CognitionImproves (the measure goes up)
Studies cited
3 studies from PubMed
- Placebo-controlled study of pramiracetam in young males with memory and cognitive problems resulting from head injury and anoxia
- Pramiracetam effects on scopolamine-induced amnesia in healthy volunteers
- Memory training and drug therapy act differently on memory and metamemory functioning: evidence from a pilot study