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White Mulberry

White mulberry is a tree whose leaves and extracts contain plant compounds that can slow tyrosinase, an enzyme involved in making the skin pigment melanin. People mostly look at it for skin pigmentation, and in one trial of 50 people with melasma, a mulberry extract oil applied to the skin improved hyperpigmentation versus placebo. The evidence is limited, resting on one small study of a topical oil rather than mulberry taken by mouth.

Sources: PMID 22052272

Best evidence
Grade C
Conditions studied
1
Outcomes
1
Graded outcomes
0010

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

1 condition

Skin Health

Skin Health: outcomes studied for White Mulberry
GradeOutcomeEffectSizeStudiesPeopleStudies list
Hyperpigmentation

Small Improvement

Improves (the measure goes down)Small effect1 study50 people

Studies that measured hyperpigmentation

Key findings

  • HyperpigmentationSkin HealthImproves (the measure goes down)

Studies cited

1 study from PubMed

  1. A comparative study of the safety and efficacy of 75% mulberry (Morus alba) extract oil versus placebo as a topical treatment for melasma: a randomized, single-blind, placebo-controlled trialJ Drugs Dermatol · PMID 22052272