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Condition

Charcot-Marie-Tooth Disease Type 1A (CMT1A)

Charcot-Marie-Tooth disease type 1A is an inherited condition of the peripheral nerves, the ones outside the brain and spinal cord, that brings gradual muscle weakness and wasting, usually starting in the feet and legs, along with numbness, tingling and high-arched feet. Little research on supplements for it has been reviewed here so far, so there are no trial findings to report yet. Vitamin D, acetyl-L-carnitine and B vitamins are the ones most often discussed, but that reflects interest rather than proven results.

Supplements studied
1
Graded outcomes
0
Trials
1
People studied
271

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Vitamin C: outcomes studied for Charcot-Marie-Tooth Disease Type 1A (CMT1A)
GradeOutcomeEffectSizeStudiesPeopleStudies list
Charcot Marie Tooth Disease SymptomsImproves (the measure goes down)1 study271 people

Studies that measured charcot marie tooth disease symptoms

The Charcot-Marie-Tooth Disease Supportive Care protocol

2 primary supplements · 7 supporting supplements

See the full protocol

Studies cited

1 study from PubMed

  1. Ascorbic acid in Charcot-Marie-Tooth disease type 1A (CMT-TRIAAL and CMT-TRAUK): a double-blind randomised trialLancet Neurol · PMID 21393063