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Colorectal Polyps

Colorectal polyps are small growths on the inner lining of the colon or rectum, and while most are harmless, some types called adenomas can slowly turn into colorectal cancer over time. Calcium and vitamin D have the most support as supplements people look at for polyps, with the evidence rated moderate for each, though little trial research on them has been reviewed here so far. Fiber and omega-3s also have moderate evidence, while the rest, such as folate, probiotics and green tea extract, rest on limited data.

Supplements studied
1
Graded outcomes
0
People studied
1,076

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Berberine: outcomes studied for Colorectal Polyps
GradeOutcomeEffectSizeStudiesPeopleStudies list
Colorectal Polyp IncidenceChanges; see studies1 study1,076 people

Studies that measured colorectal polyp incidence

The Colorectal Polyp Prevention Support protocol

2 primary supplements · 7 supporting supplements

  • Calcium1,000–1,200 mg daily with food
  • Vitamin D2,000–4,000 IU daily (maintain levels 40–60 ng/mL)

See the full protocol

Shop the evidence-backed picks

Support alongside medical care. These supplements are not a treatment for Colorectal Polyps. If you are being treated for it, talk to your clinician before adding one: supplements can interact with medicines.

Fullscript collectionGut and digestion: evidence-graded picksOpen on Fullscript

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Studies cited

1 study from PubMed

  1. Efficacy and safety of berberine in preventing recurrence of colorectal adenomas: A systematic review and meta-analysis.J Ethnopharmacol · PMID 34509605