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Condition

Dermatitis

Dermatitis, or eczema, is inflamed, red, itchy, dry skin, and the common atopic type often runs in families with allergies and asthma. Probiotics and vitamin D have the most research behind them, rated moderate, and hyaluronic acid improved skin severity in people having radiotherapy. Evidence for evening primrose oil, omega-3s and zinc is limited, and the hyaluronic acid result came from one analysis of 104 people, not everyday eczema.

Sources: PMID 35152333

Supplements studied
3
Graded outcomes
3
Trials
4
People studied
1,895

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

3 supplements

Hyaluronic Acid: outcomes studied for Dermatitis
GradeOutcomeEffectSizeStudiesPeopleStudies list
Dermatitis Severity

Moderate Improvement

Improves (the measure goes down)Moderate effect1 study104 people
Mucositis SymptomsImproves (the measure goes down)107 people
Calendula Officinalis: outcomes studied for Dermatitis
GradeOutcomeEffectSizeStudiesPeopleStudies list
Dermatitis Risk

Small Improvement

Improves (the measure goes down)Small effect3 studies756 people
Itching

Mixed effect

420 people
PainChanges; see studies420 people
Feverfew: outcomes studied for Dermatitis
GradeOutcomeEffectSizeStudiesPeopleStudies list
ErythemaImproves (the measure goes up)1 study8 people

Studies that measured erythema

Key findings

  • Dermatitis SeverityHyaluronic AcidImproves (the measure goes down)
  • Dermatitis RiskCalendula OfficinalisImproves (the measure goes down)
  • ItchingCalendula Officinalis

The Dermatitis (Eczema) Support protocol

2 primary supplements · 3 supporting supplements

  • Probiotics10–20 billion CFU daily (Lactobacillus and Bifidobacterium strains)
  • Vitamin D2,000–4,000 IU daily

See the full protocol

Shop the evidence-backed picks

Fullscript collectionSkin: evidence-graded picksOpen on Fullscript

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Studies cited

5 studies from PubMed

  1. Effect of hyaluronic acid on radiotherapy-induced mucocutaneous side effects: a meta-analysis of randomized controlled trials.Support Care Cancer · PMID 35152333
  2. Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)Inflammopharmacology · PMID 19112586
  3. Use of calendula ointment after episiotomy: a randomized clinical trial.J Matern Fetal Neonatal Med · PMID 32460565
  4. Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer.J Clin Oncol · PMID 15084618
  5. No differences between Calendula cream and aqueous cream in the prevention of acute radiation skin reactions--results from a randomised blinded trial.Eur J Oncol Nurs · PMID 23245940