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Condition

Diffuse Esophageal Spasm

Diffuse esophageal spasm is a condition in which the esophagus squeezes in an uncoordinated way instead of a smooth wave that pushes food down, causing chest pain and trouble swallowing. Peppermint oil, a smooth muscle relaxer, is the main supplement people look at, but little research on it has been reviewed here so far. Magnesium, ginger and melatonin come up too, with support mostly from how they act in the body.

Supplements studied
1
Graded outcomes
0
Trials
1
People studied
8

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Peppermint: outcomes studied for Diffuse Esophageal Spasm
GradeOutcomeEffectSizeStudiesPeopleStudies list
Diffuse Esophageal Spasm SymptomsImproves (the measure goes down)1 study8 people

Studies that measured diffuse esophageal spasm symptoms

The Diffuse Esophageal Spasm Support protocol

1 primary supplement · 3 supporting supplements

See the full protocol

Shop the evidence-backed picks

Support alongside medical care. These supplements are not a treatment for Diffuse Esophageal Spasm. If you are being treated for it, talk to your clinician before adding one: supplements can interact with medicines.

Fullscript collectionGut and digestion: evidence-graded picksOpen on Fullscript

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Studies cited

1 study from PubMed

  1. Peppermint oil improves the manometric findings in diffuse esophageal spasmJ Clin Gastroenterol · PMID 11418786