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Condition

Endocrine Function

Endocrine function describes how the body's hormone-producing glands, such as the thyroid, adrenals, pancreas and pineal gland, release chemical messengers that steer metabolism, growth, sleep and stress responses. Among supplements, the peptide epitalon has been looked at for pineal gland function, and studies found a small improvement in markers of how that gland worked. The evidence is limited, though: it rests on five small studies with 65 people in total, so it's too early to say how much this matters in daily life.

Sources: PMID 15452611; PMID 40141333

Supplements studied
0
Medicines and peptides
1
Graded outcomes
1
No supplement studies yetWe haven’t found supplement studies for Endocrine Function. The medicines and peptides studied for it are listed below.

Prescription medicines and peptides studied, for context

These are not supplements. Most need a prescription, and some are research compounds with no approved use.

1 medicine or peptide

Epitalon: outcomes studied for Endocrine Function
GradeOutcomeEffectSizeStudiesPeopleStudies list
Pineal Gland Function

Small improvement in pineal function markers

Improves (the measure goes up)Small effect5 studies65 people

Key findings

  • Pineal Gland FunctionEpitalonImproves (the measure goes up)

Studies cited

5 studies from PubMed

  1. Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising PropertiesInt J Mol Sci, 2025 · PMID 40141333
  2. Normalizing effect of the pineal gland peptides on the daily melatonin rhythm in old monkeys and elderly peopleAdv Gerontol, 2007 · PMID 17969590
  3. Pineal peptides restore the age-related disturbances in hormonal functions of the pineal gland and the pancreasExp Gerontol, 2005 · PMID 15664732
  4. Effect of peptide preparation epithalamin on circadian rhythm of epiphyseal melatonin-producing function in elderly peopleBull Exp Biol Med, 2004 · PMID 15452611
  5. Aging of the pineal glandUsp Fiziol Nauk, 2002 · PMID 12096440