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Condition

Idiopathic Asthenozoospermia

Idiopathic asthenozoospermia means sperm have reduced movement without a clear cause, which makes it harder for them to swim to and fertilize an egg. Coenzyme Q10 and L-carnitine have the most research behind them, and studies of coenzyme Q10 found sperm motility improved. That evidence is limited, though: it rests on two small studies with 22 men in total, and one was an open pilot without a comparison group.

Sources: PMID 19447425; PMID 14711549

Supplements studied
1
Graded outcomes
1
Trials
1
People studied
22

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

1 supplement

Coenzyme Q10: outcomes studied for Idiopathic Asthenozoospermia
GradeOutcomeEffectSizeStudiesPeopleStudies list
Seminal Motility

Small Improvement

Improves (the measure goes up)Small effect2 studies22 people
Sperm QualityImproves (the measure goes up)22 people

Key findings

  • Seminal MotilityCoenzyme Q10Improves (the measure goes up)

The Asthenozoospermia (Low Sperm Motility) Support protocol

2 primary supplements · 5 supporting supplements

See the full protocol

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Studies cited

2 studies from PubMed

  1. Coenzyme Q(10) supplementation in infertile men with idiopathic asthenozoospermia: an open, uncontrolled pilot studyFertil Steril · PMID 14711549
  2. Efficacy of coenzyme Q10 on semen parameters, sperm function and reproductive hormones in infertile menJ Urol · PMID 19447425