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Fang Ji

Fang Ji is a root from the Stephania tetrandra plant, used in traditional Chinese herbal medicine, that contains tetrandrine, a compound thought to influence inflammation and calcium movement in cells. In people with rheumatoid arthritis, markers of oxidative stress went down, though the evidence is limited. That came from one small study of 25 people, and lymphocyte counts showed no clear difference.

Best evidence
Grade C
Conditions studied
1
Outcomes
4
Graded outcomes
0011

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

1 condition

Rheumatoid Arthritis (RA): outcomes studied for Fang Ji
GradeOutcomeEffectSizeStudiesPeopleStudies list
Oxidative Stress Biomarkers

Small Decrease

Improves (the measure goes down)Small effect25 people
Lymphocyte Count

No effect

NoneNo effect25 people
White Blood Cell CountImproves (the measure goes up)1 study25 people

Studies that measured white blood cell count

Serum ElastaseImproves (the measure goes up)25 people

Key findings

  • Oxidative Stress BiomarkersRheumatoid Arthritis (RA)Improves (the measure goes down)
  • Lymphocyte CountRheumatoid Arthritis (RA)

Studies cited

1 study from PubMed

  1. Suppressive effects of Stephania tetrandra on the neutrophil function in patients with rheumatoid arthritisPhytother Res · PMID 15103675