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Supplement

IP6

IP6, also called inositol hexaphosphate or phytic acid, is a compound found in grains, beans, and seeds that binds minerals and takes part in cell signaling. With no single main use established, the best-supported finding is about uric acid: in one small crossover trial of 25 people with high uric acid, blood levels went down, and the evidence is limited. That is a single short study, so it needs repeating in larger groups before anyone can say how far the result holds.

Sources: PMID 31119466

Best evidence
Grade C
Conditions studied
1
Outcomes
1
Graded outcomes
0010

Evidence by condition

  • Strong
  • Moderate
  • Limited
  • Very limited

1 condition

Hyperuricemia

Hyperuricemia: outcomes studied for IP6
GradeOutcomeEffectSizeStudiesPeopleStudies list
Uric Acid

Small Decrease

Improves (the measure goes down)Small effect1 study25 people

Studies that measured uric acid

Key findings

  • Uric AcidHyperuricemiaImproves (the measure goes down)

Studies cited

1 study from PubMed

  1. Effect of Inositol Hexaphosphate (IP 6) on Serum Uric Acid in Hyperuricemic Subjects: a Randomized, Double-Blind, Placebo-Controlled, Crossover StudyPlant Foods Hum Nutr · PMID 31119466