Supplement

Pterostilbene

Pterostilbene is a plant compound found in blueberries, closely related to resveratrol, that acts as an antioxidant in the body. People mostly look at it for heart health, and in a small study of 80 people with coronary artery disease, blood pressure improved, though the evidence is limited. In 215 people, blood glucose showed no clear difference, and that evidence is very limited too.

Updated 8 November 2026
How we grade
2 studies cited

Best evidence: Grade C
Conditions studied: 5
Outcomes: 27
Graded outcomes: 0041

Evidence by condition

Strong
Moderate
Limited
Very limited

5 conditions

Coronary Artery Disease (CAD)

Coronary Artery Disease (CAD): outcomes studied for Pterostilbene
Grade	Outcome	Effect	Size	Studies	People
	Blood Pressure Small Improvement	Improves (the measure goes down)	Small effect		80 people
	Weight	Improves (the measure goes down)		1 study	80 people
Studies that measured weight Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trialEvid Based Complement Alternat Med · PMID 25057276
	High-density lipoprotein (HDL) Small Detriment	Worsens (the measure goes down)	Small effect		80 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			80 people
	Total cholesterol	Improves (the measure goes down)			80 people
	Triglycerides

High Blood Pressure

High Blood Pressure: outcomes studied for Pterostilbene
Grade	Outcome	Effect	Size	Studies	People
	Blood Pressure Small Improvement	Improves (the measure goes down)	Small effect		80 people
	Weight	Improves (the measure goes down)		1 study	80 people
Studies that measured weight Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trialEvid Based Complement Alternat Med · PMID 25057276
	High-density lipoprotein (HDL)	Improves (the measure goes up)			80 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			80 people
	Total cholesterol	Improves (the measure goes down)			80 people
	Triglycerides	Improves (the measure goes down)			80 people

High Cholesterol

Blood Pressure: improves
Weight: improves
High-density lipoprotein (HDL): improves

High Cholesterol: outcomes studied for Pterostilbene
Grade	Outcome	Effect	Size	Studies	People
	Blood Pressure Small Improvement	Improves (the measure goes down)	Small effect		80 people
	Weight	Improves (the measure goes down)		1 study	80 people
Studies that measured weight Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trialEvid Based Complement Alternat Med · PMID 25057276
	High-density lipoprotein (HDL)	Improves (the measure goes up)			80 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			80 people
	Total cholesterol	Improves (the measure goes down)			80 people
	Triglycerides	Improves (the measure goes down)			80 people

Weight Loss & Maintenance

Blood Pressure: improves
Weight: improves
High-density lipoprotein (HDL): improves

Weight Loss & Maintenance: outcomes studied for Pterostilbene
Grade	Outcome	Effect	Size	Studies	People
	Blood Pressure Small Improvement	Improves (the measure goes down)	Small effect		80 people
	Weight	Improves (the measure goes down)		1 study	80 people
Studies that measured weight Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trialEvid Based Complement Alternat Med · PMID 25057276
	High-density lipoprotein (HDL)	Improves (the measure goes up)			80 people
	Low-density lipoprotein (LDL)	Improves (the measure goes down)			80 people
	Total cholesterol	Improves (the measure goes down)			80 people
	Triglycerides	Improves (the measure goes down)			80 people

Metabolic Health

Blood glucose
Liver Enzymes: changes; see studies
Kidney Function: improves

Metabolic Health: outcomes studied for Pterostilbene
Grade	Outcome	Effect	Size	Studies	People
	Blood glucose No effect		NoneNo effect		215 people
	Liver Enzymes	Changes; see studies		1 study	215 people
Studies that measured liver enzymes Analysis of safety from a human clinical trial with pterostilbeneJ Toxicol · PMID 23431291
	Kidney Function	Improves (the measure goes up)			215 people

Key findings

Blood PressureCoronary Artery Disease (CAD)Improves (the measure goes down)
Blood glucoseMetabolic Health

Studies cited

2 studies from PubMed

Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trialEvid Based Complement Alternat Med · PMID 25057276
Analysis of safety from a human clinical trial with pterostilbeneJ Toxicol · PMID 23431291