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Does fish oil ease anxiety?

Improved a littleLimited evidenceRe-checked 8 November 2026

One trial found a modest effect. Medical students who took omega-3 fish oil for 12 weeks reported 20% fewer anxiety symptoms than those on placebo.

1 trial · 68 people · Finding: Fish Oil, Anxiety Symptoms

What the studies found

  • 12-week randomised, placebo-controlled trial, 68 students

    “Compared to controls, those students who received n-3 showed a 14% decrease in lipopolysaccharide (LPS) stimulated interleukin 6 (IL-6) production and a 20% reduction in anxiety symptoms, without significant change in depressive symptoms.”

    PubMed 21784145

The details

What the trials used
2.5 g of omega-3 a day (2,085 mg EPA and 348 mg DHA) for 12 weeks. These are the doses studied, not advice on what to take.
Who was studied
Healthy medical students with no anxiety disorder.
Worth knowing
The students had no anxiety disorder, so this trial says nothing about treating one. If anxiety is getting in the way of your life, talk to a doctor.

All the evidence for Fish Oil

Before you try it

If you take any medicine or have a health condition, ask a pharmacist or doctor before adding a supplement. This page doesn’t link to any product.

For education only, not medical advice. Talk to a qualified clinician before starting any supplement.

How we checked this

This answer comes from one finding on our site, and that finding has been re-checked: each linked study was confirmed on PubMed and read against the finding’s grade, direction and study count. We then read every abstract ourselves on 7 November 2026 and wrote the answer from them, then checked it against recent reviews; the quotes above are copied word for word. If the finding changes, this answer is hidden until it is checked again. How we grade.

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