Condition
Diabetic Foot Ulcers
Diabetic foot ulcers are open sores, usually on the sole or toes, that form when nerve damage and poor circulation from diabetes let a small injury turn into a lasting wound. The one supplement trial reviewed here gave guduchi, an Ayurvedic herb, alongside surgical care and found no clear difference in how the ulcers fared. It was a single study of 45 people, so the evidence is very limited, and wound care, pressure relief and blood sugar control stay at the center of care.
Sources: PMID 17558098
- Supplements studied
- 4
- Graded outcomes
- 2
- Trials
- 3
- People studied
- 1,033
Evidence by supplement
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Diabetic Foot Ulcers Symptoms No effect | NoneNo effect | 1 study | 45 people | |||
Studies that measured diabetic foot ulcers symptoms | ||||||
| Neutrophil Count | Improves (the measure goes up) | 45 people | ||||
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Diabetic Foot Ulcers Symptoms No effect | NoneNo effect | 45 people | ||||
| Neutrophil Count | Improves (the measure goes up) | 45 people |
Vitamin D
- Wound Healing: improves
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Wound Healing | Improves (the measure goes up) | 1 study | ||||
Studies that measured wound healing | ||||||
Calendula Officinalis
- Diabetic Foot Ulcers Symptoms: changes; see studies
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Diabetic Foot Ulcers Symptoms | Changes; see studies | 1 study | 32 people | |||
Studies that measured diabetic foot ulcers symptoms | ||||||
Key findings
- Diabetic Foot Ulcers Symptoms
The Diabetic Foot Ulcer Healing Support protocol
2 primary supplements · 7 supporting supplements
- Medical-Grade Honey (Topical)Medical-grade honey dressings (Medihoney, Manuka honey products) applied as directed by wound care team
- Zinc30–50 mg daily during active wound healing
Shop the evidence-backed picks
Support alongside medical care. These supplements are not a treatment for Diabetic Foot Ulcers. If you are being treated for it, talk to your clinician before adding one: supplements can interact with medicines.
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Studies cited
2 studies from PubMed