Condition
Tuberous Sclerosis Complex (TSD)
Tuberous sclerosis complex is a rare genetic condition in which faulty growth-control genes let non-cancerous tumors form in the brain, kidneys, heart, lungs, eyes, and skin. Little research on supplements for it has been reviewed here so far, so there are no trial findings to report. Cannabidiol has the strongest backing, since a prescription form is approved for its seizures, while the evidence for vitamin D, omega-3s, folate, and calcium is limited.
- Supplements studied
- 1
- Graded outcomes
- 0
- Trials
- 1
- People studied
- 56
Evidence by supplement
- Strong
- Moderate
- Limited
- Very limited
| Grade | Outcome | Effect | Size | Studies | People | Studies list |
|---|---|---|---|---|---|---|
| Seizure Frequency | Changes; see studies | 4 studies | 56 people | |||
The Tuberous Sclerosis Complex Supportive Care protocol
1 primary supplement · 4 supporting supplements
- Cannabidiol (CBD)Prescription required; typically 5–20 mg/kg/day
Studies cited
4 studies from PubMed
- The efficacy of cannabidiol for seizures reduction in pharmacoresistant epilepsy: a systematic review and meta-analysis.
- Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex
- Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial
- Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome