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Condition

Drug Metabolism

Drug metabolism is the way the body, mainly the liver, uses enzymes to break down medicines and other compounds so they can be used and cleared away. Black pepper's piperine has the most support here, and research found it blocked some of these enzymes and improved absorption of nutrients like CoQ10 and beta-carotene, while molybdenum saw drug clearance go up. The evidence is moderate for black pepper and limited for molybdenum, and the studies were fairly small.

Supplements studied
2
Graded outcomes
2

Evidence by supplement

  • Strong
  • Moderate
  • Limited
  • Very limited

2 supplements

Black Pepper

Black Pepper: outcomes studied for Drug Metabolism
GradeOutcomeEffectSizeStudiesPeopleStudies list
Nutrient/Drug Absorption

Piperine enhances absorption of CoQ10, beta-carotene, selenium, vitamin B6, and resveratrol via enzyme inhibition

Improves (the measure goes up)Moderate effect200 people

Molybdenum

Molybdenum: outcomes studied for Drug Metabolism
GradeOutcomeEffectSizeStudiesPeopleStudies list
Drug Clearance Rate

Small Increase

Improves (the measure goes up)Small effect80 people

Key findings

  • Nutrient/Drug AbsorptionBlack PepperImproves (the measure goes up)
  • Drug Clearance RateMolybdenumImproves (the measure goes up)

Studies cited

None of the studies we hold is linked to the Drug Metabolism outcomes on this page yet, so none is listed here. Each supplement’s page lists the studies on file for it.